Self-Injecting Methotrexate for the Treatment of Arthritis

Updated January 2024

(Example of brand name: Trexject)

Why might my doctor suggest I inject methotrexate?

This sheet is useful if your doctor has recommended injections of methotrexate to improve it's effectiveness or minimise side-effects. It gives information about how you, or a friend or family member, can safely inject methotrexate, the steps to follow and the equipment you will need. For general information on methotrexate, refer to the “Methotrexate” patient information.

The ARA have also developed a patient guide: Safe Disposal of Sharps - Information Leaflet. This patient leaflet outlines how to safely dispose of your methotrexate injection as well as highlighting links and locations where you can dispose of your sharps appropriately.